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Abstract. Repeated administration of 3,4-methylenedioxymethamphetamine (MDMA) (ecstasy) produces eccentric left ventricular (LV) dilation and diastolic dysfunction. While the mechanism (s) underlying this toxicity are unknown, oxidative stress plays an important role. MDMA is metabolized into redox cycling metabolites that produce .
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The first and most commonly used echocardiography method of LVM estimation is the linear method, which uses end-diastolic linear measurements of the interventricular septum (IVSd), LV inferolateral wall thickness, and LV internal diameter derived from 2D-guided M-mode or direct 2D echocardiography. This method utilizes the .Echocardiography Stroke volume may be derived using echocardiography from measurements of the area of the left ventricular outflow tract (LVOT) and the stroke distance. A transthoracic parasternal long axis view allows measurement of the diameter of the left ventricular outflow tract, from which one can determine the cross-sectional area .
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